Orodispersible liquisolid compacts: A novel approach to enhance solubility and bioavailability

  • P Vinoth College Of Pharmacy
  • AN Rajalakshmi College Of Pharmacy
  • P. Stephen SaiMirra Innopharm Pvt Ltd.
Keywords: Liquisolid systems, orodispersible tablets, dissolution rate, solubility

Abstract

Orodispersible liquisolid system is the combination of liquisolid technique and orodispersible system. The poor dissolution rate of water insoluble drug is a major drawback for the development of pharmaceutical dosage forms. The oral absorption of drug is most often controlled by dissolution in the gastrointestinal tract. Liquisolid system has been used to enhance dissolution rate of poorly water-soluble drugs. Orodispersible tablets are given in order to provide fast action by disperse in the mouth, without the need of water and make them compliance for paediatric and geriatric patients and to bypass the liver metabolism.

Author Biographies

P Vinoth, College Of Pharmacy

Department of Pharmaceutics, College Of Pharmacy,
Mother Theresa Postgraduate and Research Institute of Health Sciences,
Puducherry, India

AN Rajalakshmi, College Of Pharmacy

Department of Pharmaceutics, College Of Pharmacy,
Mother Theresa Postgraduate and Research Institute of Health Sciences,
Puducherry, India

P. Stephen, SaiMirra Innopharm Pvt Ltd.

Formulation Research and Development,
SaiMirra Innopharm Pvt Ltd., Chennai,
Tamil Nadu, India

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Published
2018-06-01
How to Cite
[1]
Vinoth, P., Rajalakshmi, A. and Stephen, P. 2018. Orodispersible liquisolid compacts: A novel approach to enhance solubility and bioavailability. PharmaTutor. 6, 6 (Jun. 2018), 28-35. DOI:https://doi.org/10.29161/PT.v6.i6.2018.28.
Section
Articles