In Silico Molecular Docking of Antidiabetic Agents from Medicinal Plants of Bangladesh against Glycogen Synthase Kinase

  • Nazmul Islam Prottoy Jahangirnagar University
  • Aisha Siddiqua Boby Jahangirnagar University
  • Bishajit Sarkar Jahangirnagar University
  • Asad Ullah Jahangirnagar University
  • Sohana Hossain Jahangirnagar University
Keywords: Antidiabetic, Arjunic Acid, Bangladesh, Docking, Gallic Acid, Quercetin

Abstract

Diabetes Mellitus (DM) is a metabolic disorder which affects the people of all groups around the world. Although medication is available in the market but plant derived compounds are often preferable to everyone due to their less toxicity and side effects. This study has been designed to investigate the interaction between medicinal plant derived antidiabetic agents (Arjunic acid, Quercetin and Gallic Acid) and regulatory target enzyme, Glycogen Synthase Kinase-3 Beta (GSK3B). Quercetin showed the strong interaction with the target molecule among the all compounds. However, further in vitro study is required to find out the best remedy of diabetes.

Author Biographies

Nazmul Islam Prottoy, Jahangirnagar University

Dept. of Biotechnology and Genetic Engineering
Jahangirnagar University,
Savar, Dhaka-1342, Bangladesh

Aisha Siddiqua Boby, Jahangirnagar University

Dept. of Biotechnology and Genetic Engineering
Jahangirnagar University, Savar, Dhaka-1342, Bangladesh

Bishajit Sarkar, Jahangirnagar University

Dept. of Biotechnology and Genetic Engineering
Jahangirnagar University, Savar, Dhaka-1342, Bangladesh

Asad Ullah, Jahangirnagar University

Dept. of Biotechnology and Genetic Engineering
Jahangirnagar University, Savar, Dhaka-1342, Bangladesh

Sohana Hossain, Jahangirnagar University

Dept. of Biotechnology and Genetic Engineering
Jahangirnagar University, Savar, Dhaka-1342, Bangladesh

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Published
2019-07-01
How to Cite
[1]
Prottoy, N., Boby, A., Sarkar, B., Ullah, A. and Hossain, S. 2019. In Silico Molecular Docking of Antidiabetic Agents from Medicinal Plants of Bangladesh against Glycogen Synthase Kinase. PharmaTutor. 7, 7 (Jul. 2019), 18-20.
Section
Articles

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