In Silico Molecular Docking of Antidiabetic Agents from Medicinal Plants of Bangladesh against Glycogen Synthase Kinase
Diabetes Mellitus (DM) is a metabolic disorder which affects the people of all groups around the world. Although medication is available in the market but plant derived compounds are often preferable to everyone due to their less toxicity and side effects. This study has been designed to investigate the interaction between medicinal plant derived antidiabetic agents (Arjunic acid, Quercetin and Gallic Acid) and regulatory target enzyme, Glycogen Synthase Kinase-3 Beta (GSK3B). Quercetin showed the strong interaction with the target molecule among the all compounds. However, further in vitro study is required to find out the best remedy of diabetes.
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