A Preliminary Study of Adverse Drug Reactions in a Tertiary Care Hospital of Kashmir
Purpose: To study the adverse drug reactions (ADR’s) reported from Dermatology ward in SMHS hospital of Srinagar. The adverse drug reactions were analyzed by Naranjo’s causality assessment scale and the outcomes were studied.
Methods: This observational and cross-sectional study was conducted for one month of July 2018 in an inpatient setting of Dermatology ward of SMHS hospital. The data collection was done only in Dermatology ward. Patients of all age groups and either sex were included in this study. The adverse drug reactions were assessed for their causality by performing the Naranjo’s algorithm scale. The outcomes were studied.
Result: Total 3 adverse drug reactions were reported from Dermatology ward. 20-40 years age group was studied for adverse drug reactions. The most commonly affected organ is the Skin 2 (66.66%), followed by Reproductive system 1 (33.34%).The 3 reported ADR’s were Acute Urticaria in 2 patients and Azoospermia in 1 patient. According to Naranjo’s algorithm scale, out of 3 suspected ADR’s 2 (Azoospermia: Cyclophosphamide and Acute Urticaria: Sulfasalazine) were probable and 1 suspected ADR (Acute Urticaria: Tetanus Toxoid) was possible. Out of 3 patients, 2 with Acute Urticaria recovered while as patient with Azoospermia continued with the problem during study.
Limitations: Study was conducted only in one ward i.e., Dermatology and patient number was also less.
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