Anti-Anemic Activity of Hydro-Alcoholic Extract of Fruit of Allium tricoccum in Phenylhydrazine Induced Anemic Rats

  • Deepanshu Gupta Modern institute of Pharmaceutical Sciences
  • Chandrakanta Kushwah Modern institute of Pharmaceutical Sciences
  • Ankur Joshi Modern institute of Pharmaceutical Sciences
  • Spna Malviya Modern institute of Pharmaceutical Sciences
  • Anil Kharia Modern institute of Pharmaceutical Sciences
Keywords: Anemia, anti-anemic activity, hydro-alcoholic extract, Allium tricoccum, Vit. B12

Abstract

This current research was done to bring out the anti-anemic activity in hydro-alcoholic extract of fruit of Allium tricoccum in phenylhydrazine induced anemic rats. The anemia was induced by the administration of Phenylhydrazine (60mg/kg) intraperitoneally in rats for two days. The animals were divided into 5 groups containing 6 animals each. 1st group was served as normal control group, 2nd group was served as anemic control, 3rd group was served as standard reference control administered with Vit. B12 complex, 4th group was served as test control-I administered with 100mg/kg of hydro-alcoholic extract of fruit of Allium tricoccum and 5th group was served as test control-II administered with 200mg/kg of hydro-alcoholic extract of fruit of Allium tricoccum. All the test drugs were given for 28 days daily through oral route. On 29th day blood was withdrawn, through tail puncture and subjected to the estimation of RBC, Hb and percentage Haematocrit. Both the hydro-alcoholic fruit extract of Allium tricoccum and Vit. B12 significantly increase the Haemoglobin, Red Blood Cells & percentage Haematocrit level which conclude that Allium tricoccum fruit exhibits the anti-anemic activity.

 

Author Biographies

Deepanshu Gupta, Modern institute of Pharmaceutical Sciences

Department of pharmacy,
Modern institute of Pharmaceutical Sciences
Alwasa, Indore, Madhya Pradesh, India

Chandrakanta Kushwah, Modern institute of Pharmaceutical Sciences

Department of pharmacy,
Modern institute of Pharmaceutical Sciences
Alwasa, Indore, Madhya Pradesh, India

Ankur Joshi, Modern institute of Pharmaceutical Sciences

Department of pharmacy,
Modern institute of Pharmaceutical Sciences
Alwasa, Indore, Madhya Pradesh, India

Spna Malviya, Modern institute of Pharmaceutical Sciences

Department of pharmacy,
Modern institute of Pharmaceutical Sciences
Alwasa, Indore, Madhya Pradesh, India

Anil Kharia, Modern institute of Pharmaceutical Sciences

Department of pharmacy,
Modern institute of Pharmaceutical Sciences
Alwasa, Indore, Madhya Pradesh, India

References

Gupta Deepanshu, C. Kushwah, A. Joshi, K. Malviya, S. Malviya, A. Kharia (2018) “Anti-anemic activity of hydro-alcoholic leaf extract of brassica oleracea var in phenylhydrazine induced anemic rats”; Asian Journal of Pharmaceutical Education and Research; 7(2); 86-91

Hussain Aafreen et al (2017); “Anti-anemic Activity of Seeds of Trigonella Foenum-graecum in Male Albino Rats”; J Pharm Biomed Sci; 6(11); 608-612.

Joshi Ankur, Soni Priyanka, Vyas Narendra, Khan Javed, Malviya Sapna, Kharia Anil (2017); “Anti-anemic activity of hydro alcoholic leaf extract of Aegle marmelos in phenylhydrazine induced anemic rats”; International Journal of Current Research; 9(4); 48928-48931

Joshi Ankur et al (2017) “Anti-anemic activity of hydro alcoholic leaf extract of Tamarindus Indica in phenylhydrazine induced anemic rats”; Journal of harmonized research in applied sciences; 5(3); 132-135.

Khandelwal K.R. (2013) “Practical Pharmacognosy”, 22nd ed., Nirali prakashan, Pune, 149-156.

Mohan Harsh (2005); “Textbook of pathology”; 5th edition; Jaypee Brothers, Medical publishers (p) ltd., New Delhi; 133.

Tortora J. Gerard, Derrickson Bryan (2015); “Anatomy & physiology”, 13th ed., Indian edition, Wiley India pvt. Ltd., New Delhi; 603-623.

http://www.who.int/topics/anaemia/en/ cited: 25-08-2017.

Published
2018-07-01
How to Cite
[1]
Gupta, D., Kushwah, C., Joshi, A., Malviya, S. and Kharia, A. 2018. Anti-Anemic Activity of Hydro-Alcoholic Extract of Fruit of Allium tricoccum in Phenylhydrazine Induced Anemic Rats. PharmaTutor. 6, 7 (Jul. 2018), 5-7. DOI:https://doi.org/10.29161/PT.v6.i7.2018.5.
Section
Articles

Most read articles by the same author(s)