Anti-Anemic Activity of Hydro-Alcoholic Extract Seeds of Foeniculum vulgare in Phenylhydrazine Induced Anemic Rats
Abstract
The main objective of this research was to evaluate the anti-anemic activity in hydro-alcoholic extract of seeds of Foeniculum vulgare in phenylhydrazine induced anemic rats. Phenylhydrazine (60mg/kg) was given intraperitoneally in rats for two days to induce anemia. The animals were divided into 5 groups of 6 animals each. Group 1 was known as normal control group, Group 2 was known as anemic control group, Group 3 was known as standard reference control group given with Vit. B12, Group 4 was known as test control-I given with 100mg/kg of hydro-alcoholic extract of seeds of Foeniculum vulgare, Group 5 was known as test control-II given with 200mg/kg of hydro-alcoholic extract of seeds of Foeniculum vulgare. All the test drugs were given for 28 days through oral route once in a day. On 29th day blood was taken out through tail puncture and was subjected to the determination of RBC, Hb and percentage Haematocrit. Both the hydro-alcoholic seeds extract of Foeniculum vulgare and Vit. B12 significantly increase the HB, RBC & percentage Haematocrit level which shows that Foeniculum vulgare seeds exhibits the anti-anemic activity.
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