Antimicrobial activity of Schiff Base of 2-Amino 5-Nitrothiazole and its Copper complex

  • Manjul Shrivastava Govt.M.H. College of Home Science and Science for Women
  • Garima Shrivastava Govt.M.H. College of Home Science and Science for Women
  • Gaurav Shrivastava Govt.M.H. College of Home Science and Science for Women
Keywords: Schiff base, Antimicrobial activity, Disc diffusion, Microwave assisted, Biological activity

Abstract

In an attempt to find out a new class of antimicrobial agents new schiff base ligand of 2-amino 5-nitro thiazole and its copper complex were prepared. The Microwave assisted synthesis was carried out by condensation of 2-amino 5-nitro thiazole and substituted salicyldehyde. The newly synthesized schiff base ligand and its copper complex were tested against representatives of gram-positive (Staphylococcus aureus, Bacillus subtilis) and gram- negative bacteria (E. coli, Pseudomonas putida) and fungi (Candida albicans, Aspergillus niger) by disc diffusion method.

Author Biographies

Manjul Shrivastava, Govt.M.H. College of Home Science and Science for Women

Department of Chemistry,
Govt.M.H. College of Home Science and Science for Women,
Jabalpur, MP, India

Garima Shrivastava, Govt.M.H. College of Home Science and Science for Women

Department of Chemistry,
Govt.M.H. College of Home Science and Science for Women,
Jabalpur, MP, India

Gaurav Shrivastava, Govt.M.H. College of Home Science and Science for Women

Department of Chemistry,
Govt.M.H. College of Home Science and Science for Women,
Jabalpur, MP, India

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Published
2018-09-01
How to Cite
[1]
Shrivastava, M., Shrivastava, G. and Shrivastava, G. 2018. Antimicrobial activity of Schiff Base of 2-Amino 5-Nitrothiazole and its Copper complex. PharmaTutor. 6, 9 (Sep. 2018), 1-5. DOI:https://doi.org/10.29161/PT.v6.i9.2018.1.