Antimicrobial activity of Schiff Base of 2-Amino 5-Nitrothiazole and its Copper complex
Abstract
In an attempt to find out a new class of antimicrobial agents new schiff base ligand of 2-amino 5-nitro thiazole and its copper complex were prepared. The Microwave assisted synthesis was carried out by condensation of 2-amino 5-nitro thiazole and substituted salicyldehyde. The newly synthesized schiff base ligand and its copper complex were tested against representatives of gram-positive (Staphylococcus aureus, Bacillus subtilis) and gram- negative bacteria (E. coli, Pseudomonas putida) and fungi (Candida albicans, Aspergillus niger) by disc diffusion method.
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