Glanzmann’s Thrombasthenia: A Rare Bleeding Disorder

  • Ayyagari Sri Harsha JNTUA
  • Hari Priya Mullamuri Sri Padmavathi School of pharmacy
  • Sowmya Reddy Sri Padmavathi School of pharmacy
  • Durga Prasad T S Sri Padmavathi School of pharmacy
Keywords: GT, Glanzmann’s Thrombasthenia, Clot Retraction, prolonged Bleeding Time

Abstract

Glanzmann's Thrombasthenia (GT) is a rare, autosomal recessive bleeding disorder characterized by prolonged bleeding time and impairment in aggregation of platelets and impairment in clot retraction. The physiological defect includes impairment of glycoprotein receptor’s (GPIIb/IIIa complex) present on platelet membrane which mediates platelet aggregation through fibrinogen binding. Purpose of this study is to get  all of us know about this rare condition. A 16-year old female patient presented with repeated episodes of menstrual bleeding since 4years. She was a k/c/o Glanzmann's thrombasthenia. She was treated with antifibrinolytics, IV fluids and then discharged. Early diagnosis and proper supportive care are the measures for prognosis of Glanzmann’s thrombasthenia.

Author Biographies

Hari Priya Mullamuri, Sri Padmavathi School of pharmacy

Sri Padmavathi School of pharmacy,
Jawaharlal Nehru Technological University,
Anantapuram, Andhra Pradesh, India

Sowmya Reddy, Sri Padmavathi School of pharmacy

Sri Padmavathi School of pharmacy,
Jawaharlal Nehru Technological University,
Anantapuram, Andhra Pradesh, India

Durga Prasad T S, Sri Padmavathi School of pharmacy

Sri Padmavathi School of pharmacy,
Jawaharlal Nehru Technological University,
Anantapuram, Andhra Pradesh, India

References

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Published
2019-03-01
How to Cite
[1]
Harsha, A., Mullamuri, H.P., Reddy, S. and S, D.P. 2019. Glanzmann’s Thrombasthenia: A Rare Bleeding Disorder. PharmaTutor. 7, 3 (Mar. 2019), 38-40. DOI:https://doi.org/10.29161/PT.v7.i3.2019.38.
Section
Articles