Receptor Targeting Liposomal Nano Formulations for Drug Delivery in Breast Cancer

  • Dr.Jigar Vyas Sigma Institute of Pharmacy
  • Juhi H. Patel Sigma Institute of Pharmacy
  • Ria Nitinbhai Patel Sigma Institute of Pharmacy
  • Kapil Kumar Vinodbhai Daxini Sigma Institute of Pharmacy
Keywords: liposomes, lipid Nano particles, breast cancer, multi drug resistance, Drug Delivery.

Abstract

Recently, incidences of breast cancer are increasing and it has become a leading cause of cancer related deaths of women globally. Though pharmaceutical and biotechnology industries are developing, and researchers are working to find a better treatment of breast cancer patients to improve the effectiveness of current therapy, the survival rate is very low. A lot of research is going on based on lipid particulate systems which has versatile applications for the treatment of life-threatening diseases such as breast cancer. Out of various lipid particulate systems, liposomes have been studied and explored widely as they have many applications such as improving solubility of antitumor drugs, reduces the side effects, long circulation in blood, possibility of passive and active targeting to tumor cells. Liposomal system is most popular because of its biocompatibility, capability to encapsulate hydrophilic as well as hydrophobic drugs, ease of surface modification and wide range of applications.   Thus, a thorough research is ongoing for upgradation of liposomes as multipotential carriers and its effective therapeutic. Therefore, this review article includes the recent development and techniques of liposomal nano formulations drug delivery system. This review majorly focuses on the breast cancer and its therapy, current challenges in experimental and clinical studies in liposomal formulations.   

References

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Published
2019-05-01
How to Cite
[1]
Vyas, D., Patel, J., Patel, R. and Daxini, K.K. 2019. Receptor Targeting Liposomal Nano Formulations for Drug Delivery in Breast Cancer. PharmaTutor. 7, 5 (May 2019), 1-9.
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Articles