Antacids: Heart Burn OTC Drugs

  • Tribhuvan Patel Kunwar Haribansh Singh College of Pharmacy
  • Virendra Baheliya Kunwar Haribansh Singh College of Pharmacy
  • Rajesh Prajapati Kunwar Haribansh Singh College of Pharmacy
  • Vivek Yadav Kunwar Haribansh Singh College of Pharmacy
  • Avanish Yadav Kunwar Haribansh Singh College of Pharmacy
  • Pramod Jaiswal Kunwar Haribansh Singh College of Pharmacy
Keywords: Antacids, Acid neutralizing capacity, Hyperacidity, Alkalosis

Abstract

Antacids are chemical substances which neutralizing the acid that causes heartburn. By reducing the acidity, the acid is less able to irritate the esophagus. The effect of antacids on the stomach is due to partial neutralisation of gastric hydrochloric acid and inhibition of the proteolytic enzyme, pepsin. There are commonly used self-prescribed medications.  Antacids are available many forms such as suspensions, chewable tablets and liquid gels. They consist of calcium carbonate and magnesium and aluminum salts in various compounds or combinations. Antacids are used for gastric and duodenal ulcers, gastro-oesophageal reflux disease, stress gastritis, pancreatic insufficiency, non-ulcer dyspepsia, biliary reflux, bile acid mediated diarrhoea, constipation, osteoporosis, urinary alkalinisation and chronic renal failure as a dietary phosphate binder.

Author Biographies

Tribhuvan Patel, Kunwar Haribansh Singh College of Pharmacy

Department of Pharmaceutical Sciences,
Kunwar Haribansh Singh College of Pharmacy,
Jaunpur, U.P, India

Virendra Baheliya, Kunwar Haribansh Singh College of Pharmacy

Department of Pharmaceutical Sciences,
Kunwar Haribansh Singh College of Pharmacy,
Jaunpur, U.P, India

Rajesh Prajapati, Kunwar Haribansh Singh College of Pharmacy

Department of Pharmaceutical Sciences,
Kunwar Haribansh Singh College of Pharmacy,
Jaunpur, U.P, India

Vivek Yadav, Kunwar Haribansh Singh College of Pharmacy

Department of Pharmaceutical Sciences,
Kunwar Haribansh Singh College of Pharmacy,
Jaunpur, U.P, India

Avanish Yadav, Kunwar Haribansh Singh College of Pharmacy

Department of Pharmaceutical Sciences,
Kunwar Haribansh Singh College of Pharmacy,
Jaunpur, U.P, India

Pramod Jaiswal, Kunwar Haribansh Singh College of Pharmacy

Department of Pharmaceutical Sciences,
Kunwar Haribansh Singh College of Pharmacy,
Jaunpur, U.P, India

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Published
2014-11-01
How to Cite
[1]
Patel, T., Baheliya, V., Prajapati, R., Yadav, V., Yadav, A. and Jaiswal, P. 2014. Antacids: Heart Burn OTC Drugs. PharmaTutor. 2, 11 (Nov. 2014), 16-21.