A Review: Analytical Methods for Determination of Cilnidipine in Biological Fluid and Pharmaceutical Dosage Forms

Abstract

Cilnidipine is act as a  dual blocker by blocking L- type of calcium channel present in vascular smooth muscles and  N- type of calcium channel present in sympathetic nerve  terminal that supply blood  vessels. Cilnidipine used in treatment of mostly in hypertension and various cardiovascular diseases except in Angina. Cilnidipine used alone or in combination. This review covers most recent analytical methods such as various spectroscopic methods, chromatographic methods and other methods for determination of cilnidipine in various pharmaceutical dosage forms and biological matrix were reported.