Prescribing Trend of Antihypertensive Drugs in Sri Ganganagar District: A Retrospective Study

  • Amarjeet Singh Seth G. L. Bihani S. D. College of Technical Education,
  • Sudeep Bhardwaj Seth G. L. Bihani S. D. College of Technical Education,
  • Ashutosh Aggarwal Seth G. L. Bihani S. D. College of Technical Education
Keywords: Hypertension, Prescription, Antihypertensive, Medications

Abstract

Objective: The choice of drug for the treatment of hypertension changes at short intervals. Drug utilization studies conducted at regular intervals help to guide the physician in prescribing drugs rationally. The present study was done toanalyze the prescribing patterns of antihypertensive drugs in a NorthIndian  hospital.
Material & method: A retrospective, crosssectional analysis of prescriptions of antihypertensive cases admitted in Medicine in-patient wards of civil hospital of Sri Ganganagar was conducted. All the prescription files with diagnosis ofessential hypertension were analyzed. Prescriptions for hypertension with other co-morbid conditions were also included. Frequency and proportions of utilization of antihypertensive medications were charted and figured.
Result: During the studyperiod, there were 435 prescriptions for essential hypertension. The most frequently prescribed antihypertensive medications were:  monotherapy (42.06%), (57.94%) of patients were on multiple drugtherapy, the most favored fixed drug combination being diuretics with angiotensin receptor blockers (31.74%).
Conclusion: The present study revealed that Angiotensin receptor blockers arethe drugs of choice as monotherapy and as combination therapy for hypertensives. This pattern of prescription is also supported by the current JNC VIII guidelines for the treatment of hypertension.

 

Author Biographies

Amarjeet Singh, Seth G. L. Bihani S. D. College of Technical Education,

Department of Pharmacology,
Seth G. L. Bihani S. D. College of Technical Education,
Institute of Pharmaceutical Sciences & Drug Research, Sri Ganganagar, Rajasthan, India

Sudeep Bhardwaj, Seth G. L. Bihani S. D. College of Technical Education,

Department of Pharmacology,
Seth G. L. Bihani S. D. College of Technical Education,
Institute of Pharmaceutical Sciences & Drug Research, Sri Ganganagar, Rajasthan, India

Ashutosh Aggarwal, Seth G. L. Bihani S. D. College of Technical Education

Department of Pharmacology,
Seth G. L. Bihani S. D. College of Technical Education,
Institute of Pharmaceutical Sciences & Drug Research, Sri Ganganagar, Rajasthan, India

References

1. Williams GH; Hypertensive Vascular Disease In:Harrison’s Principles of Internal Medcine. Braunwald E, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jamson JL (Eds); 15th edition; McGraw-Hill; 2001; 1414-1429.
2. Satoskar RS, Bhandarkar SD, Rege NN editors; Pharmacotherapy of Hypertension. Chapter 29, Pharmacology and Pharmacotherapeutics; 20th edition, Popular Prakashan; 2007; 402-431
3. Anand Kale, Yasmeen A. Maniyar; Prescribing Patterns of Antihypertensive Drugs in A Tertiary Care Hospital; Sch. Acad. J. Pharm.; 2013; 2(5); 416-418
4. Yuen YH, Chang S, Chong CK, Lee SC, Critchlev JA, Chan JC; Drug utilization in a hospital general medical outpatient clinic with particular reference to antihypertensive and antidiabetic drugs; J Clin Pharm Ther.; 1998; 23; 287-294.
5. Hansson L; The benefits of lowering elevated blood pressure: a critical review of studies of cardiovascular morbidity and mortality in hypertension; J Hypertens., 1996; 14; 537-544.
6. Mancia G, Grassi G; Antihypertensive treatment: past, present and future.J Hypertens; 1998; 16; S1-S7.
7. Pai G Preethi, shenoy Jnaneshwara, Sanji Narendranath; Prescribing Patterns of antihypertensive drugs in a South Indian tertiary care hospital. Drug Invention Today; 2011; 3(4); 38-40
Published
2015-04-01
How to Cite
[1]
Singh, A., Bhardwaj, S. and Aggarwal, A. 2015. Prescribing Trend of Antihypertensive Drugs in Sri Ganganagar District: A Retrospective Study. PharmaTutor. 3, 4 (Apr. 2015), 53-59.
Section
Articles