To study the Efficacy and Effects on Lipid Metabolism, anthropometry and blood pressure of Combination Treatment with ARB+HCTZ and ACEs+HCTZ in hypertensive patient

  • Rajak Sandeep Shri Guru Ram Rai Institute of Technology and Sciences
  • Kothiyal Preeti Shri Guru Ram Rai Institute of Technology and Sciences
  • Mathur Prashant Shri Guru Ram Rai Institute of Technology and Sciences
Keywords: Lipid Metabolism, Angiotensin converting enzymes, Angiotensin II receptor blocker

Abstract

Angiotensin-converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) are widely prescribed for the treatment of hypertension and heart failure, as well as for kidney disease prevention in patients with diabetes mellitus and the management of patients after myocardial infarction. Both combination therapies of an Angiotensin II receptor blocker (ARB) with the thiazide hydrochlorothiazide (HCTZ) and an Angiotensin converting enzymes (ACEs) with HCTZ are recommended to achieve blood pressure (BP) goals in antihypertensive treatment. However, although HCTZ is known to have unfavorable effects on lipid metabolism, the effects of HCTZ in the ARB+HCTZ and ACEs+HCTZ combination on lipid metabolism have not been fully elucidated. The objective of present study was “To study the Efficacy and Effects on Lipid Metabolism, anthropometry and blood pressure of Combination Treatment With ARB+HCTZ and ACEs+HCTZ in hypertensive patient.”
All prescription of hypertensive patients coming to the medicine OPD and IPD would be screened and those prescribed with  ACE-inhibitors+HCTZ and ARBs+HCTZ combination of  drugs will be selected for this study.

Author Biographies

Rajak Sandeep, Shri Guru Ram Rai Institute of Technology and Sciences

Department of clinical pharmacy,
Division of Pharmaceutical sciences,
Shri Guru Ram Rai Institute of Technology and Sciences,
Patel Nagar, Dehradun, Uttarakhand, India

Kothiyal Preeti, Shri Guru Ram Rai Institute of Technology and Sciences

Department of Pharmacology,
Division of Pharmaceutical sciences,
Shri Guru Ram Rai Institute of Technology and Sciences,
Patel Nagar, Dehradun, Uttarakhand, India

Mathur Prashant, Shri Guru Ram Rai Institute of Technology and Sciences

Department of clinical pharmacy,
Division of Pharmaceutical sciences,
Shri Guru Ram Rai Institute of Technology and Sciences,
Patel Nagar, Dehradun, Uttarakhand, India

References

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Published
2014-01-01
How to Cite
[1]
Sandeep, R., Preeti, K. and Prashant, M. 2014. To study the Efficacy and Effects on Lipid Metabolism, anthropometry and blood pressure of Combination Treatment with ARB+HCTZ and ACEs+HCTZ in hypertensive patient. PharmaTutor. 2, 1 (Jan. 2014), 112-128.
Issue
Vol 2 No 1 (2014): January 2014
Section
Articles

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