Basics of aging theories and disease related aging-an overview

  • Chandan Ghosh Bengal School of Technology
  • Abhijit De Bengal School of Technology
Keywords: Aging, Free radicals, Cancer, Diabetes


Aging is characterized by a progressive loss of physiological integrity, leading to impaired function and increased vulnerability to death. This deterioration is the primary risk factor for major human pathologies including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases. In this review, several theories and mechanisms have been put to explain the molecular basis of aging. For example, random damage of the DNA of somatic cell is believed to accumulate with increasing age. Free radicals produced during oxidation of metabolites for energy production also damage DNA and proteins.

Author Biographies

Chandan Ghosh, Bengal School of Technology

Department of Pharmaceutical Science,
Bengal School of Technology, Hooghly,
West bengal, India

Abhijit De, Bengal School of Technology

Department of Pharmaceutical Science,
Bengal School of Technology, Hooghly,
West bengal, India


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How to Cite
Ghosh, C. and De, A. 2017. Basics of aging theories and disease related aging-an overview. PharmaTutor. 5, 2 (Feb. 2017), 16-23.