In-vitro antiproliferative activity of M. Azedarach

  • Deepak Chowrasia CSJM University
  • Nisha Sharma CSJM University
  • Mohammad Arshad Lucknow University
Keywords: Cancer, Antiproliferative activity, polarity Induced extraction, MTT, M. azedarach

Abstract

Preliminary screening of different crude extract of. M. azedarach was evaluated against human cancer cell lines viz. MCF-7 (breast cancer), SaOS-2 (osteosarcoma), and A431 (epidermoid carcinoma) to search for better herbal based anticancer agent. Solvents used were water, methanol, ethanol, n-butanol, & n-hexane. It has been found that among solvents, methanolic extract of M. azedarach shows comparatively superior activity suggesting presence of phytoconstituents comprising polar functionalities.

Author Biographies

Deepak Chowrasia, CSJM University

University Institute of Pharmacy, CSJM University, Kanpur,
U.P, India

Nisha Sharma, CSJM University

University Institute of Pharmacy, CSJM University, Kanpur,
U.P., India

Mohammad Arshad, Lucknow University

Molecular Endocrinology Lab, Department of Zoology, Lucknow University,
Lucknow, U.P., India

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Published
2017-02-01
How to Cite
[1]
Chowrasia, D., Sharma, N. and Arshad, M. 2017. In-vitro antiproliferative activity of M. Azedarach. PharmaTutor. 5, 2 (Feb. 2017), 46-49.
Section
Articles