Nanocapsules: Nano novel drug delivery system
Abstract
Nano capsules are vesicular systems in which the drug is confined to a cavity consisting of an inner liquid core surrounded by a polymeric membrane. Nano capsules having various advantages and disadvantages. Preparation of Nano capsules can be used as a two types of polymers 1) Natural polymers 2) Synthetic polymers. Nano capsules are prepared by different method those are a) Solvent evaporation b) Nano precipitation c) emulsification / Solvent diffusion d) Salting out e) Dialysis f) Super critical fluid technology.
References
2.Jager A, Stefani V, Guterres SS and PohlmannAR . 2007Physico-chemical characterization of nanocapsule polymeric wall using fluorescent benzazole probes. Int J Pharm, 338(1-2), 297-305
3. Beduneau A, Saulnier P, Anton N, Hindre F, Passirani C, Rajerison H, et al. 2006Pegylatednanocapsules produced by an organic solvent free method: Evaluation of their stealth properties . Pharm. Res, 23(9), 2190-99
4. Adriana RP, Letıcia SF, Rodrigo PS, Alberto MD, Edilson VB, Tania MHC, et al. 2008Nanocapsule@xerogelmicroparticles containing sodium diclofenac: A new strategy to control the release of drugs. Int J Pharm, 358(1-2), 292-95
5.Lambert G, Fattal E, Pinto-Alphandary H, Gulik A and Couvreur . 2000Polyisobutylcyanoacrylatenanocapsules containing an aqueous core as a novel colloidal carrier for the delivery of oligonucleotides. Pharm Res, 17(6), 707-714
6. Qiang Z, Zancong S and TsunejiN . 2001 Prolonged hypoglycemic effect of insulin-loaded polybutylcyanoacrylate nanoparticles after pulmonary administration to normal rats. Int J Pharm, 218(1-2), 75-80
7. Yang H, Mendon SK and Rawlins JW . 2008 Ion of blocked isocyanates through aqueous emulsion polymerization. eXPRESS Polymer Letters, 2(5), 349-566.
8. Kimberly AD, Knut D, Magnus WL, Thomas M, Werner S, Reine W, et al. 2004 Synthesis of branched 'nanotrees' by controlled seeding of multiple branching events . Nat. Mater, 3(6), 380-384
9. Samy EM, Shautian L, Daniel G and Udo P . 1996 Synthesis of nanostructured materials using a laser vaporization condensation technique. Nanotechnology (ACS Symposium Series), 622, 79-99
10. Kensuke N, Hideaki I and YoshikiC . 2003 Temperature-dependent reversible self-assembly of gold nanoparticles into spherical aggregates by molecular recognition between pyrenyl and dinitrophenyl units. Langmuir, 19(13), 5496-501
11. Qingyi L, Feng G and DongyuanZ . 2002 The assembly of semiconductor sulfidenanocrystallites with organic reagents as templates. Nanotechnology, 13(6), 741-45
12. Zhu YQ, Hsu WK, Zhou WZ, Terrones M, Kroto HW and Walton DRM . 2001 Selective Cocatalysed growth of novel MgO fishbone fractal nanostructures. ChemPhysLett, 347(4-6), 337-343
13. Redhead HM, Davis SS and IllumL . 2001 Drug delivery in poly (lactide-co-glycolide) nanoparticles surface modified with poloxamer 407 and poloxamine 908: in vitro characterisation and in vivo evaluation. J Control Release, 70(3), 353-63

