A Review on Chalcones Synthesis and their Biological Activity

  • Shipra Verma Mahatma Gandhi P. G. College
  • Alok Kumar Srivastava Mahatma Gandhi P. G. College
  • O.P. Pandey D.D.U. Gorakhpur University
Keywords: Chalcones, synthesis, biological activity


Chalcones are a valuable molecule of medicinal importance due to presence of reactive ketoethylenic group –CO–CH=CH–, belonging to the flavonoid family. These reactive α,β-unsatutated keto function in chalcones are  responsible for their biological activity. Chalcone can be synthesized by several methods using aldehydes and ketones as starting material. This review is focused about different methods of synthesis and versatile biological activity of chalcones including antimicrobial, anticancer, antioxidant, antimalarial, antituberculosis etc.

Author Biographies

Shipra Verma, Mahatma Gandhi P. G. College

Department of Chemistry,
Mahatma Gandhi P. G. College, Gorakhpur,
U. P., India

Alok Kumar Srivastava, Mahatma Gandhi P. G. College

Department of Chemistry,
Mahatma Gandhi P. G. College, Gorakhpur,
U. P., India

O.P. Pandey, D.D.U. Gorakhpur University

Department of Chemistry,
D.D.U. Gorakhpur University, Gorakhpur,
U.P., India


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How to Cite
Verma, S., Srivastava, A.K. and Pandey, O. 2018. A Review on Chalcones Synthesis and their Biological Activity. PharmaTutor. 6, 2 (Jun. 2018), 22-39. DOI:https://doi.org/10.29161/PT.v6.i2.2018.22.