Isatin Schiff Base -An Overview

  • D Visagaperumal T. John College of Pharmacy
  • Justin Ebuka Ezekwem T. John College of Pharmacy
  • Hemaprasad Munji T. John College of Pharmacy,
  • Vineeth Chandy T. John College of Pharmacy,
Keywords: satin, Schiff base, biological activity


The review article is focused on studies of Isatin-based Schciff Bases and their biological and pharmacological activities. Isatin-based Schiff base are generally synthesized by condensation of the keto group of Isatin with different aromatic primary amines carrying imine or azomethine (–C=N–) functional group. Isatin Schciff Base possesses numerous biological properties like antitumor, antimicrobial, anti-inflammatory, anticonvulsant, antiviral, anti HIV, antioxidant, CNS depressant activities.

Author Biographies

D Visagaperumal, T. John College of Pharmacy

Department of Pharmaceutical Chemistry,
T. John College of Pharmacy,
Bangalore, Karnataka, India.

Justin Ebuka Ezekwem, T. John College of Pharmacy

Department of Pharmaceutical Chemistry,
T. John College of Pharmacy,
Bangalore, Karnataka, India.

Hemaprasad Munji, T. John College of Pharmacy,

Department of Pharmaceutical Chemistry,
T. John College of Pharmacy,
Bangalore, Karnataka, India

Vineeth Chandy, T. John College of Pharmacy,

Department of Pharmaceutical Chemistry,
T. John College of Pharmacy,
Bangalore, Karnataka, India.


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How to Cite
Visagaperumal, D., Ezekwem, J.E., Munji, H. and Chandy, V. 2018. Isatin Schiff Base -An Overview. PharmaTutor. 6, 5 (May 2018), 38-47. DOI: