A Review on Ethnopharmacological Potential of Ricinus Communis Linn.
Keywords:
Ricinus communis, Ethnopharmacology, Phytochemical Constituents
Abstract
In recent years, Ricinus communis Linn. has become a subject of interest because of its beneficial effects on human health. The present ethnopharmacological review was conducted to evaluate the therapeutic properties of Ricinus communis by scientific evidences. It belongs to the family Euphobiaceae, which is commonly known as castor. Ricinus communis is found thoughout the hotter parts of India. This plant is extensively used in Ayurveda, Unani, Siddha, Homeopathic and Allopathic system of medicine as cathartic. Traditionally this plant is used as laxative, purgative, fertilizer and fungicides etc. whereas the plant possess beneficial effects as antioxidant, antifertility, anti-inflammatory, antimicrobial, CNS stimulant, antidiabetic, insecticidal, larvicidal, antinociceptive, antiasthmatic, antiulcer, immunomodulatory, hepatoprotective, lipolytic, wound healing and central analgesic and many other medicinal properties. The extracts or the isolated compounds of this plant have been found to have potent activity against various ailments. The aim of present article is to explore the pharmacological or medicinal importance of the plant Ricinus communis linn.
References
1. Khogali A, Barakat S, Abou-Zeid H., “Isolation and identification of the phenolics from Ricinus communis L.” 1992,: Delta J. Sci. 16, 198–211.
2. Scarpa A, Guerci A., “Various uses of the castor oil plant (Ricinus communis L.): a review.” J.Ethnopharmacol. 1982, 5, 117–137.
3. Singh.R.K., Gupta.M.K., Singh.A.K. and Kumar S., “Pharmacognostical Investigation Of Ricinus Communis Stem.” IJPSR; 2010, 1(6), 89- 94.
4. Kirtikar K.R, Basu B.A. 1991. Indian Med. Plants 3, 2274–2277.
5. Dnyaneshwar J.T, Maruti G.W, Rajendra SB, Ravindra YP., “Antinociceptive activity of Ricinus communis L. Leaves”, Asian Pacific Journal of Tropical Biomedicine, 2011, 139-141.
6. Visen P, Shukla B, Patnaik G, Tripathi S, Kulshreshtha D, Srimal R, DhawanB, “Hepatoprotective activity of Ricinus communis leaves.”, Int. J. Pharmacol. 1992, 30, 241–250.
7. Capasso F, Mascolo N, Izzo AA, Gaginella TS, “Dissociation of castor oil Induced diarrhoea and intestinal mucosal injury in rat, effect of NG-nitro-Larginine methyl ester”, Br. J.Pharmacol. 1994, 113, 1127–1130.
8. Abraham Z, Bhakuni, SD, Garg HS, Goel AK, Mehrotra BN, Patnaik GK, “Screening of Indian plants for biological activity”, Indian J. Exp. Biol. 1986, 12 (24), 48–68.
9. The Wealth of India. A Dictionary of Indian Raw Material and Industrial Products, 1972, Vol-IX, 26-47.
10. Bentley R, Trimen H, Medicinal Plants, 2007,:Vol. 4: 237.
11. Government of India, Ministry of Health and Family Welfare, Department of Ayush. The Ayurvedic Pharmacopeia of India 2007; Part- ?: Vol. ?: 34- 35.
12. Eudmar Marcolino de Assis Junior, Ismael Malaquias dos Santos Fernandes, Caio Sergio Santos, Luciene Xavier de Mesquita, Rogerio Aparecido Pereira, Patricio Borges Maracaja, Benito Soto Blanco, “Toxicity of castor bean (Ricinus communis) pollen to honeybees Agriculture”, Ecosystems and Environment; 2011, 141: 221–223.
13. Encyclopedia Britanica. 2000. Castor oil. Britanica.com/bcom/eb/article/4/ 0, 57. 16, 2105+1+20724, 00htm? query=castoroil%20 oil.
14. CSIR, 1972,: The wealth of India. Raw materials. Vol. 9. Publications & Information Directorate, Council for Scientificand Industrial Research, New Delhi. 472.
15. Kadambi, K. and S.N. Dabral, “The silviculture of Ricinus communis Linn”, Indian Forester, 1955, 81(1): 53-58.
16. Jumat S., Noor D.A. M., Nazrizawati A.T., Firdaus M.Y. Mohd & Noraishah A., “Fatty Acid composition and physicochemical properties of malaysian castor bean Ricinus communis L. seed oil,” Sains Malaysiana, 2010, 39(5): 761–764.
17. Kadri A., Gharsallah N., Damak M. and Gdoura R., “Chemical composition and in vitro antioxidant properties of essential oil of Ricinus communis L.,” Journal of Medicinal Plants Research, 2011, 5(8), pp. 1466-1470.
18. Khan N. A, Dubey C. and Srivastava A., “A Triterpenoid Saponin from the Seeds of Ricinus communis,” 2010,: 14th international electronic conference on synthetic organic chemistry.
19. Kang S.S., Cordell A., Soejarto D.D., Fong H.H.S., “Alkaloids and flavonoids from Ricinus communis.” J. Nat. Prod. 1985, 48 (1), 155–156.
20. Yuldashev M.P., Batirov É.Kh., Malikov V.M., “Acylated flavanone glycosides from Ricinus communis.,” Chemistry of Natural Compounds ,1993, 29(3), pp 303-305.
21. Murthy P.S., Moorti R., Pugazhenthi S., Babu B.V., Prabhu K.M., Ratnakar P., Shukla R., Puri D., Dev G., Rusia U., Aggarwal S., “Studies with purified orally active compounds from fenugreek seeds, banyan tree bark, bittergourd fruits and garlic bulbs in diabetes mellitus, hypercholesterolemia and tuberculosis. Trends Clin. Biochem. Lab. Med.; 2003, 635–639.[8]
22. MalcolmJ. Thompson, William S. Bowers., “Lupeol and 30- norlupan-3β-ol-20-one from the coating of the castor bean (Ricinus communi L.),” phytochemistry,1968, 7, 845-847.
23. Robert B., Monica J., Bernard K., Øyvind M. A., “New anthocyanins from stem bark of castor, Ricinus communis,” Chemistry Department, Makerere University.
24. Kore K.J., Shete R.V.., Kabra M.P., Rachhadiya R.M., “Evaluation of analgesic activity of castor oil in experimental animals.,” International Journal of Universal Pharmacy and Life Sciences, 2011, 1(2).
25. Kabra M P, Rachhadiya R M. & Shete R V,“Pharmacological investigation of hydroalcholic extract of Ricinus communis leaves in arthritis induces rat,” Asian Journal of Biochemical and Pharmaceutical Research, 2011, 1 (4) ISSN: 2231-2560.
26. Saini A.K, Goya R, Gauttam V.K, Kalia A.N., “Evaluation of anti-inflammatory potential of Ricinus communis Linn leaves extracts and its flavonoids content in Wistar rats.,” J. Chem. Pharm. Res., , 2010, 2(5):690-695
27. Taur D J, Patil R Y., “Antiasthmatic activity of Ricinus communis L. Roots.,” Asian Pacific Journal of Tropical Biomedicine, 2011, S13-S16.
28. Sibi G, Kaur G, devi G, Kumar K.R.R and Mallesha H., “Anti-dandruff activity of Ricinus communis Linn. leaf extracts,” int j curr pharm res, 2012, 4 (3), 74-76.
29. Matthew O. O., Olusola L., Matthew A. O, “Preliminary Study of Hypoglycaemic and Hypolipidemic Activity of Aqueous Root Extract of Ricinus communis in Alloxan-Induced Diabetic Rats.,” J. Phys Pharm Adv, 2012, 2(10): 354-359.
30. Taur D.J, Waghmare M.G, Bandal R.S, Patil R.Y, “Antinociceptive activity of Ricinus communis L. Leaves.” Asian Pacific Journal of Tropical Biomedicine, 2011, 139-141.
31. Rachhadiya R.M, Kabra M.P, Shete R.V., “Evalution of antiulcer activity of castor oil in rats,” IJRAP, 2011, 2(4) 1349-1353.
32. Rabia N, Asghari B, “Antimicrobial potential of Ricinus communis leaf extracts in different solvents against pathogenic bacterial and fungal strains,” Asian Pac J Trop Biomed; 2012, 2(12): 944-947.
33. Ravishankar K., Indira N., Vijay Bhaskar R., “In vivo hepatoprotective activity of Ricinus communis. linn leaf extract against ccl4 induced hepatic damage in albino rats,” International Journal of Biological & Pharmaceutical Research; 2012, 3(3): 444-449.
34. Kumar A , Singh V, Ghosh S, “An experimental evalution of in vitro immunomodulatory activity of isolated compound of Ricinus communis on human neutrophils.,” International journal of green pharmacy., 2011, 5:201-4.
35. Tounou A.K, Mawussi G, Amadou S, Agboka K, Gumedzoe Y. M. D and Sanda K., Bio-insecticidal effects of plant extracts and oil emulsions of Ricinus communis L. (Malpighiales: Euphorbiaceae) on the diamondback, Plutella xylostella L. (Lepidoptera: Plutellidae) under laboratory and semi-field conditions., Journal of Applied Biosciences; 43: 2899 – 2914; ISSN 1997–5902
36. Zarai Z, Chobba I.B, Mansour R.B, Békir A, Gharsallah N, Kadri A., “Essential oil of the leaves of Ricinus communis L.: In vitro cytotoxicity and antimicrobial properties,” Lipids in Health and Disease, 2012, 11:102.
37. Singh R.K, Gupta M.K, Katiyar D, Srivastava A and Singh P., “In-Vitro Antioxidant Activity Of The Successive Extracts of Ricinus communis Stems,” 2010,: IJPSR Vol. 1, Issue 8.
2. Scarpa A, Guerci A., “Various uses of the castor oil plant (Ricinus communis L.): a review.” J.Ethnopharmacol. 1982, 5, 117–137.
3. Singh.R.K., Gupta.M.K., Singh.A.K. and Kumar S., “Pharmacognostical Investigation Of Ricinus Communis Stem.” IJPSR; 2010, 1(6), 89- 94.
4. Kirtikar K.R, Basu B.A. 1991. Indian Med. Plants 3, 2274–2277.
5. Dnyaneshwar J.T, Maruti G.W, Rajendra SB, Ravindra YP., “Antinociceptive activity of Ricinus communis L. Leaves”, Asian Pacific Journal of Tropical Biomedicine, 2011, 139-141.
6. Visen P, Shukla B, Patnaik G, Tripathi S, Kulshreshtha D, Srimal R, DhawanB, “Hepatoprotective activity of Ricinus communis leaves.”, Int. J. Pharmacol. 1992, 30, 241–250.
7. Capasso F, Mascolo N, Izzo AA, Gaginella TS, “Dissociation of castor oil Induced diarrhoea and intestinal mucosal injury in rat, effect of NG-nitro-Larginine methyl ester”, Br. J.Pharmacol. 1994, 113, 1127–1130.
8. Abraham Z, Bhakuni, SD, Garg HS, Goel AK, Mehrotra BN, Patnaik GK, “Screening of Indian plants for biological activity”, Indian J. Exp. Biol. 1986, 12 (24), 48–68.
9. The Wealth of India. A Dictionary of Indian Raw Material and Industrial Products, 1972, Vol-IX, 26-47.
10. Bentley R, Trimen H, Medicinal Plants, 2007,:Vol. 4: 237.
11. Government of India, Ministry of Health and Family Welfare, Department of Ayush. The Ayurvedic Pharmacopeia of India 2007; Part- ?: Vol. ?: 34- 35.
12. Eudmar Marcolino de Assis Junior, Ismael Malaquias dos Santos Fernandes, Caio Sergio Santos, Luciene Xavier de Mesquita, Rogerio Aparecido Pereira, Patricio Borges Maracaja, Benito Soto Blanco, “Toxicity of castor bean (Ricinus communis) pollen to honeybees Agriculture”, Ecosystems and Environment; 2011, 141: 221–223.
13. Encyclopedia Britanica. 2000. Castor oil. Britanica.com/bcom/eb/article/4/ 0, 57. 16, 2105+1+20724, 00htm? query=castoroil%20 oil.
14. CSIR, 1972,: The wealth of India. Raw materials. Vol. 9. Publications & Information Directorate, Council for Scientificand Industrial Research, New Delhi. 472.
15. Kadambi, K. and S.N. Dabral, “The silviculture of Ricinus communis Linn”, Indian Forester, 1955, 81(1): 53-58.
16. Jumat S., Noor D.A. M., Nazrizawati A.T., Firdaus M.Y. Mohd & Noraishah A., “Fatty Acid composition and physicochemical properties of malaysian castor bean Ricinus communis L. seed oil,” Sains Malaysiana, 2010, 39(5): 761–764.
17. Kadri A., Gharsallah N., Damak M. and Gdoura R., “Chemical composition and in vitro antioxidant properties of essential oil of Ricinus communis L.,” Journal of Medicinal Plants Research, 2011, 5(8), pp. 1466-1470.
18. Khan N. A, Dubey C. and Srivastava A., “A Triterpenoid Saponin from the Seeds of Ricinus communis,” 2010,: 14th international electronic conference on synthetic organic chemistry.
19. Kang S.S., Cordell A., Soejarto D.D., Fong H.H.S., “Alkaloids and flavonoids from Ricinus communis.” J. Nat. Prod. 1985, 48 (1), 155–156.
20. Yuldashev M.P., Batirov É.Kh., Malikov V.M., “Acylated flavanone glycosides from Ricinus communis.,” Chemistry of Natural Compounds ,1993, 29(3), pp 303-305.
21. Murthy P.S., Moorti R., Pugazhenthi S., Babu B.V., Prabhu K.M., Ratnakar P., Shukla R., Puri D., Dev G., Rusia U., Aggarwal S., “Studies with purified orally active compounds from fenugreek seeds, banyan tree bark, bittergourd fruits and garlic bulbs in diabetes mellitus, hypercholesterolemia and tuberculosis. Trends Clin. Biochem. Lab. Med.; 2003, 635–639.[8]
22. MalcolmJ. Thompson, William S. Bowers., “Lupeol and 30- norlupan-3β-ol-20-one from the coating of the castor bean (Ricinus communi L.),” phytochemistry,1968, 7, 845-847.
23. Robert B., Monica J., Bernard K., Øyvind M. A., “New anthocyanins from stem bark of castor, Ricinus communis,” Chemistry Department, Makerere University.
24. Kore K.J., Shete R.V.., Kabra M.P., Rachhadiya R.M., “Evaluation of analgesic activity of castor oil in experimental animals.,” International Journal of Universal Pharmacy and Life Sciences, 2011, 1(2).
25. Kabra M P, Rachhadiya R M. & Shete R V,“Pharmacological investigation of hydroalcholic extract of Ricinus communis leaves in arthritis induces rat,” Asian Journal of Biochemical and Pharmaceutical Research, 2011, 1 (4) ISSN: 2231-2560.
26. Saini A.K, Goya R, Gauttam V.K, Kalia A.N., “Evaluation of anti-inflammatory potential of Ricinus communis Linn leaves extracts and its flavonoids content in Wistar rats.,” J. Chem. Pharm. Res., , 2010, 2(5):690-695
27. Taur D J, Patil R Y., “Antiasthmatic activity of Ricinus communis L. Roots.,” Asian Pacific Journal of Tropical Biomedicine, 2011, S13-S16.
28. Sibi G, Kaur G, devi G, Kumar K.R.R and Mallesha H., “Anti-dandruff activity of Ricinus communis Linn. leaf extracts,” int j curr pharm res, 2012, 4 (3), 74-76.
29. Matthew O. O., Olusola L., Matthew A. O, “Preliminary Study of Hypoglycaemic and Hypolipidemic Activity of Aqueous Root Extract of Ricinus communis in Alloxan-Induced Diabetic Rats.,” J. Phys Pharm Adv, 2012, 2(10): 354-359.
30. Taur D.J, Waghmare M.G, Bandal R.S, Patil R.Y, “Antinociceptive activity of Ricinus communis L. Leaves.” Asian Pacific Journal of Tropical Biomedicine, 2011, 139-141.
31. Rachhadiya R.M, Kabra M.P, Shete R.V., “Evalution of antiulcer activity of castor oil in rats,” IJRAP, 2011, 2(4) 1349-1353.
32. Rabia N, Asghari B, “Antimicrobial potential of Ricinus communis leaf extracts in different solvents against pathogenic bacterial and fungal strains,” Asian Pac J Trop Biomed; 2012, 2(12): 944-947.
33. Ravishankar K., Indira N., Vijay Bhaskar R., “In vivo hepatoprotective activity of Ricinus communis. linn leaf extract against ccl4 induced hepatic damage in albino rats,” International Journal of Biological & Pharmaceutical Research; 2012, 3(3): 444-449.
34. Kumar A , Singh V, Ghosh S, “An experimental evalution of in vitro immunomodulatory activity of isolated compound of Ricinus communis on human neutrophils.,” International journal of green pharmacy., 2011, 5:201-4.
35. Tounou A.K, Mawussi G, Amadou S, Agboka K, Gumedzoe Y. M. D and Sanda K., Bio-insecticidal effects of plant extracts and oil emulsions of Ricinus communis L. (Malpighiales: Euphorbiaceae) on the diamondback, Plutella xylostella L. (Lepidoptera: Plutellidae) under laboratory and semi-field conditions., Journal of Applied Biosciences; 43: 2899 – 2914; ISSN 1997–5902
36. Zarai Z, Chobba I.B, Mansour R.B, Békir A, Gharsallah N, Kadri A., “Essential oil of the leaves of Ricinus communis L.: In vitro cytotoxicity and antimicrobial properties,” Lipids in Health and Disease, 2012, 11:102.
37. Singh R.K, Gupta M.K, Katiyar D, Srivastava A and Singh P., “In-Vitro Antioxidant Activity Of The Successive Extracts of Ricinus communis Stems,” 2010,: IJPSR Vol. 1, Issue 8.
Published
2014-03-05
How to Cite
[1]
Preeti, K. and Verma, A.B. 2014. A Review on Ethnopharmacological Potential of Ricinus Communis Linn. PharmaTutor. 2, 3 (Mar. 2014), 76-85.
Section
Articles
