Heparin: Powerful and Instantaneously Acting Anticoagulant
Keywords:
Heparin, anticoagulant, plasma antithrombin III
Abstract
Anticoagulant is an agent that is used to prevent the formation of blood clots. Anticoagulants, such as heparin or warfarin work on chemical reactions in the body to lengthen the time it takes to form a blood clot. Heparin the anticoagulant drug that is used to prevent blood clots from forming during and after surgery and to treat various heart, lung, and circulatory disorders in human body. Heparin is comparatively a strong acid that forms water–soluble salts. It is used in treatment of venous thrombosis and its extensions, pulmonary embolism (PE), peripheral arterial embolism. Smoking and alcohol may alter response to heparin. Abrupt withdrawal of heparin may precipitate increased coagulability.
References
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2. MEDICINAL CHEMISTRY BY ASUTOSH KAR::4TH EDITION; 2006;Page 887-889
3. heparinscience.com/molecular_weight.html
4. 1657.A to Z Drug Facts (A to Z Drug Facts, 4th ed) by David S. Tatro and Facts and Comparisons
5. Oster JR, et al. Heparin-induced aldosterone suppression and hyperkalemia.Am J Med 1995; 98: 575–86.
6. Walker AM, Jick H. Predictors of bleeding during heparin therapy.JAMA 1980; 244: 1209–12.
7. CSM. Heparin-induced thrombocytopenia. Current Problems 28 1990. Also available at: mhra.gov.uk/home/ idcplg?IdcService=GET_FILE&dDocName=CON2024446& RevisionSelectionMethod=LatestReleased (accessed 22/05/08)
8. Sonnenblick M, et al. Hyper-transaminasemia with heparin therapy.BMJ 1975; 3: 77.
Published
2014-11-01
How to Cite
[1]
Ray, A. 2014. Heparin: Powerful and Instantaneously Acting Anticoagulant. PharmaTutor. 2, 11 (Nov. 2014), 30-34.
Section
Articles
