Mitomycin C: A Useful Anticancer Drug
Keywords:
Mitomycin, Cytotoxic chemotherapy, Cancer
Abstract
Cancer is basically a disease of cells characterized by a shift in the control mechanism which is associated with cell differentiation. In most cases causes of cancer is multifactorial. Cancer is the second most causes of death after heart disease. Cytotoxic chemotherapy for cancer offers cure for only certain type of cancer. Chemotherapy may prolong the life. Chemotherapy provides palliative rather than curative therapy at present.
References
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2. Corrie PG, Pippa G. (2008). "Cytotoxic chemotherapy: clinical aspects". Medicine 36 (1): 24–28. doi:10.1016/j.mpmed.2007.10.012.
3. cancer.gov/drugdictionary?CdrID=42674
4. Danshiitsoodol N, de Pinho CA, Matoba Y, Kumagai T, Sugiyama M (2006). "The mitomycin C (MMC)-binding protein from MMC-producing microorganisms protects from the lethal effect of bleomycin: crystallographic analysis to elucidate the binding mode of the antibiotic to the protein". J Molec Biol 360 (2): 398–408. doi:10.1016/j.jmb.2006.05.017. PMID 16756991.
5. Cummings J et al. Eur J Cancer 1995; 31A: 1928-33
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2. Corrie PG, Pippa G. (2008). "Cytotoxic chemotherapy: clinical aspects". Medicine 36 (1): 24–28. doi:10.1016/j.mpmed.2007.10.012.
3. cancer.gov/drugdictionary?CdrID=42674
4. Danshiitsoodol N, de Pinho CA, Matoba Y, Kumagai T, Sugiyama M (2006). "The mitomycin C (MMC)-binding protein from MMC-producing microorganisms protects from the lethal effect of bleomycin: crystallographic analysis to elucidate the binding mode of the antibiotic to the protein". J Molec Biol 360 (2): 398–408. doi:10.1016/j.jmb.2006.05.017. PMID 16756991.
5. Cummings J et al. Eur J Cancer 1995; 31A: 1928-33
6. 1657.A to Z Drug Facts (A to Z Drug Facts, 4th ed) by David S. Tatro and Facts and Comparisons.
Published
2014-11-01
How to Cite
[1]
Ray, A. 2014. Mitomycin C: A Useful Anticancer Drug. PharmaTutor. 2, 11 (Nov. 2014), 56-58.
Section
Articles
