Phytochemical Screening & Evaluation of Antimicrobial Activity of Glycyrrhiza Glabra Linn

  • D.K Vir Nimar Institute of Pharmacy
  • Pankaj Kushwah Nimar Institute of Pharmacy
  • Nandu Kayande Nimar Institute of Pharmacy
  • Ravina Patidar Nimar Institute of Pharmacy
Keywords: Antimicrobial, phytochemical screening, Glycyrrhiza Glabra, microorganism

Abstract

The present study was undertaken to explore the phytochemical screening & antimicrobial activity of stems of Glycyrrhiza Glabra L. (Leguminaceae). Glycyrrhiza Glabra L. were screened for their antimicrobial activity by agar well diffusion method, standard screening method & disc diffusion method. In the phytochemical screening showed presence of secondary metabolites, flavonides, glycosides & terpenoids. It is also showed potent against almost all the test organism.

Study indicate that Glycyrrhiza Glabra has antibacterial, antioxidant, antimalerial, antispasmodic, anti-inflammatory and anti-hyper glycemic properties. Various other effects like antiulcer, antiviral, antihapatotoxic, antifungal and herpes simplex have also been studies. One of the most commonly reported side effects with licorice supplementation is elevated blood pressure.

Author Biographies

D.K Vir, Nimar Institute of Pharmacy

Department of Pharmacology
Nimar Institute of Pharmacy,
Dhamnod, Dhar. M.P,India

Pankaj Kushwah, Nimar Institute of Pharmacy

Department of Pharmacognosy,
Nimar Institute of Pharmacy,
Dhar, M.P, India

Nandu Kayande, Nimar Institute of Pharmacy

Department of Pharmacology
Nimar Institute of Pharmacy,
Dhamnod, Dhar. M.P,India

Ravina Patidar, Nimar Institute of Pharmacy

Department of Pharmacology
Nimar Institute of Pharmacy,
Dhamnod, Dhar. M.P,India

References

1. ncbi.org.
2.Rambir Singh, Ramesh Chandrqa Mridula Bose and Pratibha Mehta Luthra “Antibactreial activity of Glycyrrhiza Glabra L.extract on pathogenic bacteria”, current science, 83.2002,737.
3.T.V. Sambasivam Pillai, Dictionary of Medicine, Chemistry, Botany & Allied science, 3rd volume, P.No. 212-217.
4.Bukar, A., Uba A. and Oyeyi, T.I. Antimicrobial profile of morinaoleifera lam. Extracts against some food borne microorganisms, Bayero Journal of Pure and Applied Sciences, 3(1), 2010 43-48.
5. cellbiolabs.com.
6.K.M. Elizabeth, Antimicrobial Activity of Tamarindus indica Linn. Indian Journal of Clinical Biochemistry, 2005, 20 (2), 150-153.
7.Vedpriya Arya, Sanjay Yadv, Sandeep Kumar, JP Yadav, Antimicrobial activity of cassia occidentals L (leaf) against various Human Pathogenic microbes, Life Sciences and Medicine Research. 2010, 1-6.
8. ncbi.com.
9.Anonymous 2009 mmbr.asm.org/cgi/pmidlookup?view=long&pmid=3083222.
10.R.C. Dubey & D.K. Maheshwari, A textbook of Microbiology, 3rd edition P.No.49-50.
11.S.U. Kummmaru, T. and Santosh H. Morphological diversity and its distribution. P.No. 441-416.
12.C.K. Kokate, S.K. Purohit, Gohhale D.K. Text book of Pharmacognosy, 3rd ed., Published by Nirali Prakashan Pvt. Ltd. P.No.181-183.
13.Harbone J.B., Phytochemical methods, 3rd ed., 1990, Published by Hall Londen, P.No. 123-131.
14.Segal R, Pisanty S, Wormser R, Azaz E and Sela MN, Anticariogenic activity of licorice and Glycyrrhizine I: Inhibition of in vitro plaque formation by Streptococcus mutants. Journal of Pharmaceutical Sciences. 1985; 74: 79-81.
15.Ravikumar Patil H.s, Makari, H.K. Gurumurthy H., In Vitro antimicrobial activity of Ethanol Extract of Glycyrrhiza Glabra L. EJEAF Che, 6 (9), 2007, 2318-2322.
16. whfoods.com.
17.Baba M, Shigeta S. Antiviral activity of glycyrrhizin against Varicella zoster virus in vitro .Antiviral Res 1987, 107.
18.Fenwick, G., Lutomski, J. and Nieman, C. (1990): Glycyrrhiza Glabra L. (Liquorice): Composition uses and analysis. Food Chemistry., 38(2): 119-143.
19.Nakagawa K and Asami M, Effect of glycyrrhizin on hepatic lysosomal system. Japanese Journal of Pharmacology, 1981; 31: 849–851.
Published
2014-05-01
How to Cite
[1]
Vir, D., Kushwah, P., Kayande, N. and Patidar, R. 2014. Phytochemical Screening & Evaluation of Antimicrobial Activity of Glycyrrhiza Glabra Linn. PharmaTutor. 2, 5 (May 2014), 144-147.
Section
Articles