Antiulcer Activity of Annona Squamosa Seed Extract in Experimental Rats
Keywords:
Annona squamosa, anti-ulcer, Pylorus ligation
Abstract
Antiulcer activity of aqueous extracts of Annona squamosa seed extract was studied in Rats by pyloric ligation method. The extract at dose of 100,200 mg/kg produced significant inhibition of gastric lesion induced by Pylorus ligation induced ulcer. The parameters taken to assess anti-ulcer activity were volume of gastric secretion, PH, free acidity, total acidity and ulcer index. The results indicate that the alcoholic extract significantly (P < 0.001) decreases the volume of gastric acid secretion, PH, free acidity, total acidity and ulcer index with respect to control.
References
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2. Dinesh kumar patidar.”Anti-ulcer activity of aqueous extract of murraya koenigii in albino rats”. International Journal of Pharma and Bio Sciences.Vol-2 Issue1.
3. CH. Madhu, P. Jonathan Brainard, G. Prithvi Raj, J. Swapn and A. Samba Siva Rao.” Anti ulcer activity of aqueous extract of annona squamosa leaves on rats”. IJPSR, 2012; Vol. 3(11): 4429-4433 .
4. Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy, NiraliPrakashan; 39th edi. Aug. 2007. 284-285.
5.Swati S. Kansara, Manmohan Singhal.” Evaluation of Antiulcer Activity of Moringa Oleifera Seed Extract”. JPSBR: Volume 3, Issue 1: Jan Feb 2013 (20-25).
6. Sengupta Mohua, Mondal Palash Saha (Das) Mitz, Paul Suhrita,Gupta Mradu. “Evaluation of anti-ulcer activity of aqueous extract of black cumin Seeds (nigella sativa l) on experimental albino rats”. Journal of Drug Delivery & Therapeutics; 2013, 3(1), 25-28.
7.Ramesh Alluri, Anil Kumar Sagi, Praveen Kumar Pasala.”Evaluation of gastric antiulcer and antioxidant activities in aqueous extracts of annona squamosa and achyranthes aspera in rats.” International Journal of Phytopharmacology. 2(2), 2011, 66-69.
Published
2014-06-01
How to Cite
[1]
Kushwah, P. and Kayande, N. 2014. Antiulcer Activity of Annona Squamosa Seed Extract in Experimental Rats. PharmaTutor. 2, 6 (Jun. 2014), 174-176.
Section
Articles
